Introduction

Mycotoxins are a group of structurally diverse secondary metabolites of fungi that occur as contaminants of grains worldwide. Aspergillus, Alternaria, Claviceps, Fusarium, and Penicillium species of fungi are universal in nature and under ideal conditions often infect economically important crops and forages in the field, during storage, shipment, and processing. Many of the secondary metabolites produced by these fungi can cause serious health problems in animals and their presence in agricultural commodities may result in serious economic losses. Effects of mycotoxin contamination, in livestock, may include reduction in performance such as feed intake, body weight gain, and feed efficiency as well as increased susceptibility to disease.

A typical poultry ration is made up of several grain sources; each of which may be contaminated with a different mycotoxin or more than one mycotoxin. When more than one mycotoxin is present in a diet, the effects can either be additive, synergistic, or antagonistic.

A number of approaches have been evaluated to deal with mycotoxin contaminated poultry feeds. For binding of these toxins there is need of broad spectrum of toxin binder, Which would also impart some nutritive value along with the binding effect on toxins.

We are pleased to launch HBC- BIO, a broad-spectrum toxin binder with a nutritive value to counter the toxicity problem in feed.

HBC-BIO contains

a) HSCAS & Na-Bentonite

HSCAS & Bentonites can adsorb & retains 95% aflatoxins. They are made of two or more mineral-oxide layers, which are parallely stacked units of Silica & Aluminum sheets. Cations present on clay are exchangeable. HSCAS & Na-Bentonite (negative charge) has high CEC (high exchange capacity) to bind aflatoxins molecule (positive charge).

HBC- BIO Contains all the silicates in perfect combination .All the silicates are subjected to a special heat treatment during manufacturing process which enhances its ionic properties to ensure increased & strong electromagnetic charges & irreversible binding with toxins. Strong & irreversible bond ensures complete adsorption of toxins in the feed. The irreversible bond is very strong & will not get disintegrated in the aqueous environment of gut. As a result the complex formed between HSCAS & Toxin gets excreted out of gastrointestinal tract. The thermodynamically treated HSCAS has selective & High Cationic exchange activity.

ORGANIC ACIDS -

Organic acids are lipid soluble so that they are able to enter the microbial cell. Once in the cell, the acid releases the proton in the more alkaline environment, resulting in a decrease of intracellular pH. This influences microbial metabolism inhibiting the action of important microbial enzymes and forces the bacterial cell to use energy to release protons, leading to an intracellular accumulation of acid anions. Organic acids exert their antimicrobial action both in the feed and in the GI-tract of bird. For better binding of aflatoxins with HSCAS the organic acids provide acidic medium.

Organic acids increases palatability of feed, thereby better consumption of feed. Better-feed consumption enhances better production.

Activated charcoal –

It is universal toxin binder effectively adsorbs Ochratoxins, T2 toxin & other mycotoxins.

It acts through:
Adsorption
Mechanical filtration
Ion exchange
Surface oxidation

HBC-BIO contains activated charcoal, which is obtained by burning coconut kernels. It is subjected to a special heat treatment during the process of manufacture. Charcoal obtained from coconut kernel is the best source of charcoal, which ensures additional adsorption property.

MOS -

MOS is derived from the outer yeast cell wall of Saccharomyces cerevisiae. MOS has numerous different & easy accessible adsorption centers. One gram of MOS can bind 2.7 mg Zearalenone and other toxins. MOS also eliminates bacterial toxins by blocking colonization of pathogens. It eliminates harmful bacteria’s ( salmonella, e.coli etc.) from digestive tract

Bacillus Subtilis -

Bacillus Subtilis binds aflatoxin-producing fungi. It produces small cyclic polypeptides, which have activity against bacteria & Aspergilus genus fungi. It produces quality amylase thereby it adds the nutritive value to HBC-bio.

Bacillius Subtilius is a microorganism which synthesizes Anti-fungal peptides, which binds toxins produced by Aspergillus genus.

The cell wall components of ingested Bacillus Subtilis are able to activate nearly all systems of the immune defense, including the activation of at least three specific antibodies (IgM, IgG and IgA secretion), which inhibits growth of E.coli, Salmonella etc.