| Tretenoin (USP
- 24, BP-2000) |
 |
|
All trans-retinoic
acid
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic
acid
(C20H28O2 ); Mol. Wt. = 300.44 |
|
| Retinoic acid |
Appearance
|
|
crystalline powder |
Color
|
|
yellow or light orange |
Clarity of a 2% soln.
In Chloroform
|
|
clear to almost clear
;
max. 3.0 FTU |
Melting point
|
|
180.0 - 184.0 0 C |
Identification
|
|
corresponds |
UV absorption in IPA
acidified with hydrochloric acid Max : wavelength
A ( 1% , 1cm)
|
|
351.0 - 355.0 nm
1455 - 1545 |
Loss on drying
|
|
max. 0.50 %
|
Sulfated ash
|
|
max. 0.10% |
Heavy metals
|
|
max. 20 ppm |
Related substances
|
|
corresponds |
Organic impurities
Isotretenoin Unknown impurities
|
|
max. 2.00 %
total max. 0.50 % |
Photo isomers
|
|
complies |
Assay (dried)
|
|
98.5 - 101.0 % |
Stability
|
|
stable at room temperature
in closed Containers. May decompose when exposed to light. |
CAS No
|
|
302 - 79 - 4 |
|
|
|
